I use AutoHotKey to make it extremely easy to auto-magically talk to USB devices plugged into my laptop.

Once I plug a USB device (like a SAM32) into my laptop, I press Windows Key + c and the serial console will automatically connect to the proper COM port and I can begin interfacing with the device.

The script looks like this:

#c::
COMPort := Object()
COMPortName := Object()
Num:=0
Loop, HKLM, HARDWARE\\DEVICEMAP\\SERIALCOMM\\
{
    RegRead, OutputVar
    If not InStr("%OutputVar%", "COM3")
      Run "putty.exe" "-serial" "%OutputVar%" "115200"
      Exit
    COMPort%Num%:=OutputVar
    COM_result:=COMPort%Num%
    Num+=1
}
Return

it requires you have PuTTy installed and a putty.exe executable in %systemroot%